https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47544 Wed 22 Mar 2023 15:52:30 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47837 n = 330), annual transition probabilities were obtained between no/mild (Expanded Disability Status Scale (EDSS) levels 0-3.5), moderate (EDSS 4-6.0) and severe (EDSS 6.5-9.5) disability. Results: From no/mild disability, 6.4% (95% confidence interval (CI): 4.7-8.4) and 0.1% (0.0-0.2) progressed to moderate and severe disability annually, respectively. From moderate disability, 6.9% (1.0-11.4) improved (to no/mild state) and 2.6% (1.1-4.5) worsened. From severe disability, 0.0% improved to moderate and no/mild disability. Male sex, age at onset, longer disease duration, not using immunotherapies greater than 3 months and a history of relapse were related to higher probabilities of worsening. Conclusion: We have estimated probabilities of changing disability levels in Australians with RRMS. Probabilities differed between various subgroups, but due to small sample sizes, results should be interpreted with caution. Our findings will be helpful in predicting long-term disease outcomes and in health economic evaluations of MS.]]> Wed 01 Feb 2023 15:34:54 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43091 Tue 13 Sep 2022 12:26:49 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43333 Thu 15 Sep 2022 14:57:26 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32799 Thu 09 Dec 2021 11:02:52 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7617 10 sunburns ever compared with no sunburns ever). Silicone casts of the dorsum of the hand provide a measure of cumulative UVR dose and number of sunburns over the lifetime, which persists after adjustment for chronological age. They can be used as an objective measure of cumulative past sun exposure in epidemiologic studies, but other determinants of skin damage, such as skin pigmentation, should be concurrently evaluated.]]> Sat 24 Mar 2018 08:34:44 AEDT ]]>